Client News |
Please find below a list of selected recent news and press releases from Bio-Link’s clients. |
Bio-Link client Actinogen Medical announced that an independent Data Safety and Monitoring Board completed a planned interim analysis of its phase II Alzheimer’s trial of Xanamem and recommended continuation of the trial without modification (link), together with a $15M placement by leading investors including biotechnology value fund (link). Learn more about Xanamem.
The first two patients have been dosed in a phase Ib clinical trial at the Princess Alexandra Hospital (PAH, Brisbane, Australia), evaluating the efficacy of co-treatment of the anti-psychotic / anti-emetic drug prochlorperazine (Stemetil®) with anti-EGFR monoclonal antibody (mAb) cetuximab in head and neck squamous cell carcinoma (HNSCC) patients (HREC/16/QPAH/825). Prochlorperazine is a potent off-target inhibitor of the enzyme dynamin II. To learn more, please click here.
Oncology Venture, a precision oncology biopharmaceutical company and Bio-Link client, has recently announced important milestones in the development of its phase I/II immuno-oncology drug candidate APO010, granting of a key US patent for phase II ready drug candidate irofulven, and validation of its platform precision medicine technology, Drug Response Predictor™ (DRP™):
Oncology Venture’s immuno-oncology drug APO010, a first-in-class FAS-ligand, will be tested in a subset of Multiple Myeloma patients identified as likely responders by the Drug Response Predictor (DRPTM) precision medicine technology. Read Full Story Here
Neural Diagnostics Pty Ltd, a Melbourne-based medtech developer, have been awarded $2.2M in a 2nd round CRC-P grant to develop their EVestG™ technology for medical applications in the field of head trauma. The project is a collaboration with GE Healthcare and Monash University that is expected to be completed in 3 years at a total expenditure of $8.1M.
EVestG™ (ElectroVestibuloGraphy) is a novel technology and medical device that enables a simple, non-invasive test for the objective and accurate classification of a range of neurological diseases, including Alzheimer’s, Parkinson’s, autism spectrum disorder, bipolar disorder, depression, Ménière’s disease, schizophrenia and concussion. Potential applications for EVestG™ range from streamlining development of CNS drugs to clinical diagnostics to workplace safety and more.
CRC-Ps are a stream of the Australian CRC Programme in which a small group of collaborators work on a single, short term, industry-identified and industry-led collaborative research project to develop a product, service or process that will solve problems for business and deliver tangible outcomes.
Neural Diagnostics have engaged Bio-Link to facilitate business development and strategic partnerships for EVestG™.
Oncology Venture has announced that the first patient with metastatic breast cancer included in its LiPlaCis™ extension – proof of concept trial has obtained a confirmed Partial Remission (ie >30% tumour reduction) (press release link). The patient is the first of 12-15 patients whose tumour tissue has been pre-screened as a highly likely responder by Oncology Venture’s Drug Response Predictor (DRP™). Bio-Link is seeking partners to co-develop or secure rights to LiPlaCis™. Click here for full press release.
The Children’s Medical Research Institute has won a record-breaking A$10 million grant from the Australian Cancer Research Foundation. The A$10 million grant is one of the largest grants for medical research equipment in Australian history and will be used to establish The ACRF International Centre for the Proteome of Cancer (ProCan) at the Children’s Medical Institute in Westmead. The centre will be working to analyse tens of thousands of samples of cancer for precise protein levels in small biopsies. In phase two of the project, advanced computer analysis will compare the protein data with already available data for each cancer, providing a major step forward for cancer diagnosis and treatment. For more information, please see the press release.
Children’s Cancer Institute in conjunction with Sydney Children’s Hospital Network have launched an Australian first initiative to treat high-risk child cancer patients with patient specific tailored treatments. According to many birth defect attorneys, the program Zero Childhood Cancer is focused on detailed laboratory analysis on each child’s unique cancer cells to help identify which treatment is best suited for their specific cancer once they are diagnosed after birth which could potentially result in death. If a loved one has passed away, then you may want to contact a wrongful death law firm for legal assistance and afterwards you may need to hire funeral services.
The goal of this program is to achieve a 100% survival rate in childhood cancer in the future. Please see CCI’s press release here.
Thе Pаtіеnt-Cеntrеd Research Nеtwоrk, оr PACER nеtwоrk, fосuѕеѕ оn dеvеlоріng thе еvіdеnсе аbоut patient priorities аnd values аnd еѕtаblіѕhіng mеаnіngful partnerships with раtіеntѕ and саrеgіvеrѕ.
Pаtіеnt-сеntrеd care іѕ widely аdvосаtеd as fundаmеntаl tо healthcare delivery асrоѕѕ Auѕtrаlіа and internationally. Onе оf PACER’ѕ goals іѕ tо dіrесt rеѕеаrсh in thіѕ ѕаmе direction and to bеttеr align scientific evidence wіth whаt іѕ important to patients.
Cо-fоundеr оf the PACER Network, Aѕѕосіаtе Prоfеѕѕоr Allіѕоn Tоng, ѕроkе аt thе lаunсh еvеnt аt Kіdѕ Research аbоut thе сruсіаl role rеѕеаrсhеrѕ hаvе tо рlау іn contributing to thіѕ gоаl.
“Thеrе іѕ ѕtrоng еvіdеnсе оf a mіѕmаtсh between thе outcomes fаvоurеd by hеаlth care providers аnd patients. Wе, аѕ researchers, nееd to іdеntіfу thе priorities аnd needs of раtіеntѕ аnd thеіr fаmіlіеѕ, аnd сhооѕе tорісѕ аnd оutсоmеѕ that аrе іmроrtаnt tо thеm,” ѕhе said.
Chandana Guhа, carer tо hеr daughter, рrоvіdеd іnѕіght іntо thе раtіеnt jоurnеу. Shе tаlkеd аbоut how rеѕеаrсh саn brіng hоре іn tіmеѕ of desperation, and the nееd for research tо арреаl tо the immediate nееdѕ оf patients аnd families.